hla b27 psoriasisra hla b27psoriatic arthritis hla b27psoriatic arthritis treatmentrheumatoid arthritiseronegative rheumatoid arthritispsoriatic arthritis autoimmune diseasedmards rheumatoid arthritisrheumatoid arthritis neuropathyrheumatoid arthritis hereditarytofacitinib rheumatoid arthritisupadacitinib rheumatoid arthritis