mthfr and methylfolatemthfr psychiatric disordersmthfr deficiency depressionmthfr and autoimmune disordersmthfr deficiency pregnancysevere mthfr deficiencymthfr mutation and depressionmthfr genetic disordermthfr depression anxietymthfr c677t depressionmthfr folate deficiencymethylfolate dosage mthfr